| Primary information |
|---|
| ID | 31448 |
| Uniprot ID | P10276 |
| Description | Retinoic acid receptor alpha;RAR-alpha;Alternative Name- Nuclear receptor subfamily 1 group B member 1 |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | Phosphorylated. Phosphorylation does not change during cell cycle. Phosphorylation on Ser-77 is crucial for transcriptional activity. |
| Function | This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression. |
| Length | 462 |
| Molecular Weight | 50771 |
| Reference | NA |
| Hormone | NA |
| PDB ID | 1DKF; 1DSZ;
|