Primary information |
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ID | 31431 |
Uniprot ID | O19052 |
Description | Peroxisome proliferator-activated receptor gamma;PPAR-gamma;Alternative Name- Nuclear receptor subfamily 1 group C member 3 |
Organism | Oryctolagus cuniculus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular Location | Nucleus |
Developmental Stage | NA |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Post Translational Modification | NA |
Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand; the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. |
Length | 475 |
Molecular Weight | 54365 |
Reference | NA |
Hormone | 1044 |
PDB ID | NA
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