Detailed description page of Hmrbase2

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31422 details
Primary information
ID31422
Uniprot IDQ0ZAQ8
DescriptionPeroxisome proliferator-activated receptor delta;PPAR-delta;Alternative Name- PPAR-beta;Alternative Name- Nuclear receptor subfamily 1 group C member 2
OrganismCanis familiaris
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular LocationNucleus
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionReceptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand; the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Decreases expression of NPC1L1 once activated by a ligand.
Length441
Molecular Weight49776
ReferenceNA
Hormone1044
PDB IDNA