Primary information |
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ID | 31422 |
Uniprot ID | Q0ZAQ8 |
Description | Peroxisome proliferator-activated receptor delta;PPAR-delta;Alternative Name- PPAR-beta;Alternative Name- Nuclear receptor subfamily 1 group C member 2 |
Organism | Canis familiaris |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular Location | Nucleus |
Developmental Stage | NA |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Post Translational Modification | NA |
Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand; the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Decreases expression of NPC1L1 once activated by a ligand. |
Length | 441 |
Molecular Weight | 49776 |
Reference | NA |
Hormone | 1044 |
PDB ID | NA
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