Primary information |
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ID | 31421 |
Uniprot ID | P37232 |
Description | Peroxisome proliferator-activated receptor alpha;PPAR-alpha;Alternative Name- Nuclear receptor subfamily 1 group C member 1 |
Organism | Xenopus laevis |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular Location | Nucleus |
Developmental Stage | Oocytes; embryos; and adults. |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Post Translational Modification | NA |
Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand; the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. |
Length | 474 |
Molecular Weight | 52856 |
Reference | NA |
Hormone | 1036; 1044 |
PDB ID | NA
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