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31421 details
Primary information
ID31421
Uniprot IDP37232
DescriptionPeroxisome proliferator-activated receptor alpha;PPAR-alpha;Alternative Name- Nuclear receptor subfamily 1 group C member 1
OrganismXenopus laevis
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular LocationNucleus
Developmental StageOocytes; embryos; and adults.
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionReceptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand; the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.
Length474
Molecular Weight52856
ReferenceNA
Hormone1036; 1044
PDB IDNA