Primary information |
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ID | 31418 |
Uniprot ID | P23204 |
Description | Peroxisome proliferator-activated receptor alpha;PPAR-alpha;Alternative Name- Nuclear receptor subfamily 1 group C member 1 |
Organism | Mus musculus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular Location | Nucleus |
Developmental Stage | It appears first at 13.5 dpc and increases until birth. |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Post Translational Modification | NA |
Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand; the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. |
Length | 468 |
Molecular Weight | 52347 |
Reference | NA |
Hormone | 1036; 1044 |
PDB ID | NA
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