| Primary information |
|---|
| ID | 31417 |
| Uniprot ID | Q07869 |
| Description | Peroxisome proliferator-activated receptor alpha;PPAR-alpha;Alternative Name- Nuclear receptor subfamily 1 group C member 1 |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | NA |
| Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand; the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. |
| Length | 468 |
| Molecular Weight | 52225 |
| Reference | NA |
| Hormone | 1036; 1044 |
| PDB ID | 1I7G; 1K7L; 1KKQ; 2NPA; 2P54; 2REW;
|