| Primary information |
|---|
| ID | 31414 |
| Uniprot ID | Q66JK1 |
| Description | Nuclear receptor subfamily 6 group A member 1;Alternative Name- Germ cell nuclear factor;GCNF |
| Organism | Xenopus tropicalis |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Silurana. |
| Subcellular Location | Cytoplasm. Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the nuclear hormone receptor family. NR6 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | NA |
| Function | Probable orphan nuclear receptor. Binds to a response element containing repeats of the motif 5'-AGGTCA-3'. Required for anterior-posterior patterning during organogenesis. Acts with chordin to play a role in patterning the midbrain-hindbrain. Isoform Em is required for integrin-mediated cell matrix interaction during neurulation and for the morphogenetic movements leading to formation of the neural tube. Also mediates the effect of retinoic acid on primary neurogenesis. |
| Length | 435 |
| Molecular Weight | 50010 |
| Reference | NA |
| Hormone | NA |
| PDB ID | NA
|