Detailed description page of Hmrbase2

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31397 details
Primary information
ID31397
Uniprot IDP22829
DescriptionNuclear receptor subfamily 4 group A member 1;Alternative Name- Orphan nuclear receptor HMR;Alternative Name- Nerve growth factor-induced protein I-B;NGFI-B;Alternative Name- NUR77
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationNucleus
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationPhosphorylation of Ser-350 results in decrease in NBRE binding while phosphorylation of Ser-340 has little effect on it.
FunctionProbable nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'.
Length597
Molecular Weight64282
ReferenceNA
HormoneNA
PDB ID1CIT; 1YJE;