Primary information |
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ID | 31397 |
Uniprot ID | P22829 |
Description | Nuclear receptor subfamily 4 group A member 1;Alternative Name- Orphan nuclear receptor HMR;Alternative Name- Nerve growth factor-induced protein I-B;NGFI-B;Alternative Name- NUR77 |
Organism | Rattus norvegicus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular Location | Nucleus |
Developmental Stage | NA |
Similarity | Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Post Translational Modification | Phosphorylation of Ser-350 results in decrease in NBRE binding while phosphorylation of Ser-340 has little effect on it. |
Function | Probable nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'. |
Length | 597 |
Molecular Weight | 64282 |
Reference | NA |
Hormone | NA |
PDB ID | 1CIT; 1YJE;
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