Detailed description page of Hmrbase2

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31383 details
Primary information
ID31383
Uniprot IDQ9Y466
DescriptionNuclear receptor subfamily 2 group E member 1;Alternative Name- Nuclear receptor TLX;Alternative Name- Protein tailless homolog;Tll;hTll
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationNucleus
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionOrphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development.
Length385
Molecular Weight42589
ReferenceNA
HormoneNA
PDB IDNA