| Primary information |
|---|
| ID | 31377 |
| Uniprot ID | Q505F1 |
| Description | RecName- Nuclear receptor subfamily 2 group C member 1;Alternative Name- Orphan nuclear receptor TR2;Alternative Name- Testicular receptor 2;mTR2 |
| Organism | Mus musculus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular Location | Nucleus (Potential) |
| Developmental Stage | Isoform 1 is highly expressed in early to midgestation embryos; with expression leveling off during stage E15. After birth; expression in the testes remains at a basal level until puberty; begins to increase at postnatal day 16 and peaks at postnatal days 20 to 24. Expression is maintained at a high |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | NA |
| Function | Orphan nuclear receptor. Isoform 1 represses transcription and binds DNA as a homodimer. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. |
| Length | 590 |
| Molecular Weight | 65506 |
| Reference | NA |
| Hormone | NA |
| PDB ID | NA
|