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31371 details
Primary information
ID31371
Uniprot IDQ8MIM3
DescriptionRecName- Nuclear receptor subfamily 1 group I member 3;Alternative Name- Constitutive androstane receptor;CAR
OrganismMacaca mulatta
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular LocationNucleus
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionBinds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Length352
Molecular Weight39923
ReferenceNA
HormoneNA
PDB IDNA