| Primary information |
|---|
| ID | 31370 |
| Uniprot ID | Q14994 |
| Description | RecName- Nuclear receptor subfamily 1 group I member 3;Alternative Name- Constitutive androstane receptor;CAR;Alternative Name- Constitutive activator of retinoid response;Constitutive active response |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | NA |
| Function | Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. |
| Length | 352 |
| Molecular Weight | 39942 |
| Reference | NA |
| Hormone | NA |
| PDB ID | 1XV9; 1XVP;
|