Detailed description page of Hmrbase2

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31343 details
Primary information
ID31343
Uniprot IDQ9BG96
DescriptionRecName- Nuclear receptor subfamily 0 group B member 1;Alternative Name- Nuclear receptor DAX-1;
OrganismPongo pygmaeus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo.
Subcellular LocationNucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytopla
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR0 subfamily.
Post Translational ModificationNA
FunctionOrphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.
Length470
Molecular Weight51780
ReferenceNA
HormoneNA
PDB IDNA