Primary information |
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ID | 31340 |
Uniprot ID | Q61066 |
Description | RecName- Nuclear receptor subfamily 0 group B member 1;Alternative Name- Nuclear receptor DAX-1; |
Organism | Mus musculus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular Location | Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytopla |
Developmental Stage | Expressed in E5.5 throughout the embryo except in the proximal visceral endoderm. |
Similarity | Belongs to the nuclear hormone receptor family. NR0 subfamily. |
Post Translational Modification | NA |
Function | Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency. |
Length | 472 |
Molecular Weight | 52576 |
Reference | NA |
Hormone | NA |
PDB ID | NA
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