Detailed description page of Hmrbase2

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31340 details
Primary information
ID31340
Uniprot IDQ61066
DescriptionRecName- Nuclear receptor subfamily 0 group B member 1;Alternative Name- Nuclear receptor DAX-1;
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationNucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytopla
Developmental StageExpressed in E5.5 throughout the embryo except in the proximal visceral endoderm.
SimilarityBelongs to the nuclear hormone receptor family. NR0 subfamily.
Post Translational ModificationNA
FunctionOrphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.
Length472
Molecular Weight52576
ReferenceNA
HormoneNA
PDB IDNA