Detailed description page of Hmrbase2

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31328 details
Primary information
ID31328
Uniprot IDP79404
DescriptionRecName- Mineralocorticoid receptor;MR;Alternative Name- Nuclear receptor subfamily 3 group C member 2; Fragment;
OrganismSus scrofa
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular LocationCytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Cytoplasmic an
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR3 subfamily.
Post Translational ModificationPhosphorylated.
FunctionReceptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Length164
Molecular Weight19695
ReferenceNA
Hormone1126
PDB IDNA