Detailed description page of Hmrbase2

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31316 details
Primary information
ID31316
Uniprot IDP79926
DescriptionRecName- Hepatocyte nuclear factor 4-beta;HNF-4-beta;Alternative Name- Nuclear receptor subfamily 2 group A member 3;
OrganismXenopus laevis
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular LocationNucleus
Developmental StageMaternal protein which is distributed within an animal-to-vegetal gradient in the embryo. Present from the egg stage onward and throughout the entire development.
SimilarityBelongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionTranscription factor; binds and activates the promoter for the HNF1-alpha gene. Seems to have a lower DNA binding activity than HNF4-alpha and is a weaker transactivator than the alpha isoform.
Length446
Molecular Weight50257
ReferenceNA
HormoneNA
PDB IDNA