Detailed description page of Hmrbase2

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31315 details
Primary information
ID31315
Uniprot IDQ91766
DescriptionRecName- Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Alternative Name- Nuclear receptor subfamily 2 group A member 1;
OrganismXenopus laevis
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular LocationNucleus
Developmental StageMaternal protein which is distributed within an animal-to-vegetal gradient in the embryo. Present throughout the entire development.
SimilarityBelongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionTranscription factor; binds and activates the promoter for the HNF1-alpha gene. Potential initiator of a transcriptional cascade within a subset of cells committed to a specific developmental program. Could be a determinant for asymmetry in early development.
Length464
Molecular Weight51967
ReferenceNA
HormoneNA
PDB IDNA