| Primary information |
|---|
| ID | 31255 |
| Uniprot ID | P03372 |
| Description | RecName- Estrogen receptor;ER;Alternative Name- Estradiol receptor;Alternative Name- ER-alpha;Alternative Name- Nuclear receptor subfamily 3 group A member 1; |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Nucleus |
| Developmental Stage | NA |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | Phosphorylated by cyclin A/CDK2. Phosphorylation probably enhances transcriptional activity. Glycosylated; contains N-acetylglucosamine; probably O- linked. |
| Function | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
| Length | 595 |
| Molecular Weight | 66216 |
| Reference | NA |
| Hormone | 1001; 1024; 1025; 1027; 1034; 1035; 1036; 1038; 10 |
| PDB ID | 1A52; 1AKF; 1ERE; 1ERR; 1G50; 1GWQ; 1GWR; 1HCP; 1H |