Detailed description page of Hmrbase2

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31242 details
Primary information
ID31242
Uniprot IDQ6QMY5
DescriptionRecName- Steroid hormone receptor ERR1;Alternative Name- Estrogen-related receptor; alpha;ERR-alpha;Alternative Name- Nuclear receptor subfamily 3 group B member 1;
OrganismCanis familiaris
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular LocationNucleus
Developmental StageNA
SimilarityBelongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationPhosphorylated (Probable).
FunctionBinds to an ERR-alpha response element (ERRE) containing a single consensus half-site; 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus.
Length422
Molecular Weight45457
ReferenceNA
HormoneNA
PDB IDNA