| Primary information |
|---|
| ID | 31237 |
| Uniprot ID | P34021 |
| Description | RecName- Ecdysone receptor;Alternative Name- Ecdysteroid receptor;Alternative Name- 20-hydroxy-ecdysone receptor;20E receptor;Alternative Name- EcRH;Alternative Name- Nuclear receptor subfamily 1 grou |
| Organism | Drosophila melanogaster |
| Txonomy | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular Location | Nucleus |
| Developmental Stage | In the salivary glands of mid instar larvae levels increase during puff stage 1 at 86-94 hours of development then remain relatively constant until the premetamorphic pulse of ecdysone in late larvae. Levels diminish dramatically from puff stage 7 onwards. Levels increase in the prepupal period duri |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | NA |
| Function | Receptor for ecdysone. Binds to ecdysone response elements (ECRES) following ecdysone-binding; and recruitment of a complex containing the histone methyltransferase trr; leads to activate transcription of target genes. |
| Length | 878 |
| Molecular Weight | 93853 |
| Reference | NA |
| Hormone | 1053 |
| PDB ID | 1R0N; 1R0O; 2HAN;
|