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31229 details
Primary information
ID31229
Uniprot IDP17671
DescriptionRecName- Ecdysone-induced protein 75B; isoforms C/D;Alternative Name- E75-A;Alternative Name- Nuclear receptor subfamily 1 group D member 3; isoforms C/D;
OrganismDrosophila melanogaster
TxonomyEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular LocationNucleus (Potential)
Developmental StageIn mid instar larvae salivary glands; low basal levels are observed in puff stage 1. Levels increase in late larvae from puff stages 3-10; then decrease abruptly at stage 11. In prepupae; isoform C is the predominant form during the transition between puff stages 18-19. At puff stage 1; expression i
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionImplicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.
Length1199
Molecular Weight128534
ReferenceNA
Hormone1053
PDB IDNA