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31228 details
Primary information
ID31228
Uniprot IDP13055
DescriptionRecName- Ecdysone-induced protein 75B; isoform B;Alternative Name- E75-C;Alternative Name- Nuclear receptor subfamily 1 group D member 3; isoform B;
OrganismDrosophila melanogaster
TxonomyEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular LocationNucleus (Potential)
Developmental StageIn mid instar larvae salivary glands; levels increase during puff stage 1; then remain relatively constant until the premetamorphic pulse of ecdysone at puff stage 5. Levels increase again in late larvae at puff stages 9-10. At puff stage 1 expression is also seen in the gut. Levels are low in the g
SimilarityBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post Translational ModificationNA
FunctionImplicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.
Length1412
Molecular Weight151292
ReferenceNA
Hormone1053
PDB IDNA