| Primary information |
|---|
| ID | 31227 |
| Uniprot ID | P17672 |
| Description | RecName- Ecdysone-induced protein 75B; isoform A;E75-B;Alternative Name- Nuclear receptor subfamily 1 group D member 3; isoform A; |
| Organism | Drosophila melanogaster |
| Txonomy | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular Location | Nucleus (Potential) |
| Developmental Stage | In mid instar larvae salivary glands; levels are low during puff stage 1; increase during puff stages 2-4 and diminish from stage 5 onwards. In prepupae; isoform A is the predominant form during puff stage 19 and the transition to stage 20. By stage 3 it is present in the gut; Malpighian tubules and |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Post Translational Modification | NA |
| Function | Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone. |
| Length | 1355 |
| Molecular Weight | 147171 |
| Reference | NA |
| Hormone | 1053 |
| PDB ID | NA
|