| Primary information |
|---|
| ID | 31195 |
| Uniprot ID | Q9PVZ4 |
| Description | Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR) (XTK-1b)[Contains- Insulin receptor subunit alpha; Insulin receptor subunitbeta]. |
| Organism | Xenopus laevis |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular Location | Cell membrane; Single-pass type I membrane protein |
| Developmental Stage | Expressed both maternally and zygotically. Weakly expressed in embryos through gastrulation and neurulation. Expressed in the tailbud stage and in older tadpoles. |
| Similarity | Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. Contains 3 fibronectin type-III domains. Contains 1 protein kinase domain. |
| Post Translational Modification | Autophosphorylated on tyrosine residues in response to insulin. |
| Function | This receptor binds insulin and has a tyrosine-protein kinase activity. May be required for forelimb regeneration. |
| Length | 1362 |
| Molecular Weight | 153757 |
| Reference | NA |
| Hormone | P12706; P12707 |
| PDB ID | NA
|