Primary information |
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ID | 31186 |
Uniprot ID | Q9HBX9 |
Description | Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-richrepeat-containing G-protein coupled receptor 7). |
Organism | Homo sapiens |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular Location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | NA |
Similarity | Belongs to the G-protein coupled receptor 1 family. Contains 1 LDL-receptor class A domain. Contains 10 LRR (leucine-rich) repeats. |
Post Translational Modification | NA |
Function | Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. |
Length | 757 |
Molecular Weight | 86993 |
Reference | NA |
Hormone | P04090; P04808; Q8WXF3 |
PDB ID | 2JM4;
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