Detailed description page of Hmrbase2

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31186 details
Primary information
ID31186
Uniprot IDQ9HBX9
DescriptionRelaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-richrepeat-containing G-protein coupled receptor 7).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; Multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family. Contains 1 LDL-receptor class A domain. Contains 10 LRR (leucine-rich) repeats.
Post Translational ModificationNA
FunctionReceptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Length757
Molecular Weight86993
ReferenceNA
HormoneP04090; P04808; Q8WXF3
PDB ID2JM4;