Detailed description page of Hmrbase2

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31159 details
Primary information
ID31159
Uniprot IDQ8WXD0
DescriptionRelaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-richrepeat-containing G-protein coupled receptor 8) (G-protein coupledreceptor affecting testicular descent) (G-protein coupled receptor
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; Multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family. Contains 1 LDL-receptor class A domain. Contains 10 LRR (leucine-rich) repeats.
Post Translational ModificationNA
FunctionReceptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
Length754
Molecular Weight86453
ReferenceNA
HormoneP04090; P04808; Q8WXF3
PDB IDNA