Detailed description page of Hmrbase2

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31108 details
Primary information
ID31108
Uniprot IDQ61606
DescriptionGlucagon receptor precursor (GL-R).
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationCell membrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 2 family.
Post Translational ModificationNA
FunctionThis is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Length485
Molecular Weight54872
ReferenceNA
HormoneP55095
PDB IDNA