Detailed description page of Hmrbase2

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31106 details
Primary information
ID31106
Uniprot IDQ60748
DescriptionCorticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2)(Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH-R2).
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationMembrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 2 family.
Post Translational ModificationNA
FunctionThis is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I; II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Length431
Molecular Weight49923
ReferenceNA
HormoneQ8CIT0
PDB ID1U34; 2JNC; 2JND;