Primary information |
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ID | 31106 |
Uniprot ID | Q60748 |
Description | Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2)(Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH-R2). |
Organism | Mus musculus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular Location | Membrane; multi-pass membrane protein |
Developmental Stage | NA |
Similarity | Belongs to the G-protein coupled receptor 2 family. |
Post Translational Modification | NA |
Function | This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I; II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
Length | 431 |
Molecular Weight | 49923 |
Reference | NA |
Hormone | Q8CIT0 |
PDB ID | 1U34; 2JNC; 2JND;
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