Primary information |
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ID | 31091 |
Uniprot ID | Q49LX6 |
Description | Somatostatin receptor type 2 (SS2R). |
Organism | Canis familiaris |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular Location | Cell membrane; multi-pass membrane protein |
Developmental Stage | NA |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Post Translational Modification | NA |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells; this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
Length | 369 |
Molecular Weight | 41293 |
Reference | NA |
Hormone | P49670 |
PDB ID | NA
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