Detailed description page of Hmrbase2

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31073 details
Primary information
ID31073
Uniprot IDQ16671
DescriptionAnti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30)(Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIStype II receptor) (MISRII) (MRII).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationMembrane; single-pass type I membrane protein
Developmental StageNA
SimilarityBelongs to the Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 protein kinase domain.
Post Translational ModificationNA
FunctionOn ligand binding; forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate; then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Length573
Molecular Weight62750
ReferenceNA
HormoneP03971
PDB IDNA