Detailed description page of Hmrbase2

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31072 details
Primary information
ID31072
Uniprot IDQ13324
DescriptionCorticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2)(Corticotropin-releasing hormone receptor 2) (CRH-R 2).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationMembrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 2 family.
Post Translational ModificationNA
FunctionThis is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I; II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Length411
Molecular Weight47688
ReferenceNA
HormoneP06850
PDB IDNA