Detailed description page of Hmrbase2

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31047 details
Primary information
ID31047
Uniprot IDP47871
DescriptionGlucagon receptor precursor (GL-R).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 2 family.
Post Translational ModificationNA
FunctionThis is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Length477
Molecular Weight54009
ReferenceNA
HormoneP01275
PDB IDNA