| Primary information |
|---|
| ID | 31045 |
| Uniprot ID | P47799 |
| Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
| Organism | Equus caballus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
| Subcellular Location | Membrane; multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
| Post Translational Modification | N-glycosylated; indirectly required for FSH-binding; possibly via a conformational change that allows high affinity binding of hormone. |
| Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Among all mammalian FSH receptors; on the horse receptor does not bind LH/chorionic gonadotrophin (CG). |
| Length | 694 |
| Molecular Weight | 78005 |
| Reference | NA |
| Hormone | P01220; P01226 |
| PDB ID | NA
|