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31039 details
Primary information
ID31039
Uniprot IDP35378
DescriptionFollicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor).
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationMembrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats.
Post Translational ModificationN-glycosylated; indirectly required for FSH-binding; possibly via a conformational change that allows high affinity binding of hormone.
FunctionReceptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Length692
Molecular Weight77769
ReferenceNA
HormoneP01216; Q60687
PDB IDNA