| Primary information |
|---|
| ID | 31017 |
| Uniprot ID | P30968 |
| Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Membrane; multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Post Translational Modification | NA |
| Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act a an inhibitor of GnRH-R signaling. |
| Length | 328 |
| Molecular Weight | 37731 |
| Reference | NA |
| Hormone | O43555; P01148; Q6X4W1 |
| PDB ID | NA
|