| Primary information |
|---|
| ID | 31011 |
| Uniprot ID | P30874 |
| Description | Somatostatin receptor type 2 (SS2R) (SRIF-1). |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular Location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Post Translational Modification | NA |
| Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells; this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
| Length | 369 |
| Molecular Weight | 41333 |
| Reference | NA |
| Hormone | P61278 |
| PDB ID | NA
|