Detailed description page of Hmrbase2

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31009 details
Primary information
ID31009
Uniprot IDP30872
DescriptionSomatostatin receptor type 1 (SS1R) (SRIF-2).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionReceptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
Length391
Molecular Weight42686
ReferenceNA
HormoneP61278
PDB IDNA