Detailed description page of Hmrbase2

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31007 details
Primary information
ID31007
Uniprot IDP30680
DescriptionSomatostatin receptor type 2 (SS2R) (SRIF-1).
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationCell membrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionReceptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells; this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.
Length369
Molecular Weight41200
ReferenceNA
HormoneP60042
PDB IDNA