| Primary information |
|---|
| ID | 31005 |
| Uniprot ID | P30553 |
| Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular Location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Post Translational Modification | NA |
| Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety; analgesia; arousal; and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Length | 452 |
| Molecular Weight | 48957 |
| Reference | NA |
| Hormone | P01355; P04563 |
| PDB ID | NA
|