| Primary information |
|---|
| ID | 30992 |
| Uniprot ID | P21463 |
| Description | Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormonereceptor). |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular Location | Membrane; multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 8 LRR (leucine-rich) repeats. |
| Post Translational Modification | NA |
| Function | Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5). |
| Length | 764 |
| Molecular Weight | 86475 |
| Reference | NA |
| Hormone | P04652; Q925Q4 |
| PDB ID | NA
|