Primary information |
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ID | 30985 |
Uniprot ID | P16471 |
Description | Prolactin receptor precursor (PRL-R). |
Organism | Homo sapiens |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular Location | Membrane; Single-pass type I membrane protein. Secreted. Note=Isoform 7 |
Developmental Stage | NA |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains. |
Post Translational Modification | NA |
Function | This is a receptor for the anterior pituitary hormone prolactin. Isoforms 4 and 6 are unable to transduce prolactin signaling. |
Length | 622 |
Molecular Weight | 69506 |
Reference | NA |
Hormone | P01236 |
PDB ID | 1BP3; 3D48;
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