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30976 details
Primary information
ID30976
Uniprot IDO62772
DescriptionCorticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1)(Corticotropin-releasing hormone receptor 1) (CRH-R 1).
OrganismOvis aries
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular LocationMembrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 2 family.
Post Translational ModificationC-terminal Ser or Thr residues may be phosphorylated.
FunctionThis is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Length415
Molecular Weight47559
ReferenceNA
HormoneP01142
PDB IDNA