| Primary information |
|---|
| ID | 30950 |
| Uniprot ID | P79222 |
| Description | Calcitonin receptor precursor (CT-R). |
| Organism | Oryctolagus cuniculus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
| Subcellular Location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | NA |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Post Translational Modification | NA |
| Function | This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Isoform 2 has altered ligand binding and abolished coupling to phospholipase C. |
| Length | 474 |
| Molecular Weight | 55235 |
| Reference | NA |
| Hormone | NA |
| PDB ID | NA
|