Detailed description page of Hmrbase2

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30794 details
Primary information
ID30794
Uniprot IDQ8UUY8
DescriptionBeta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor).
OrganismOncorhynchus mykiss
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular LocationCell membrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationLacks the regulatory protein kinase A phosphorylation sites within the G-protein binding domain that mediate desensitization and are present in mammalian homologs.
FunctionBeta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Length409
Molecular Weight45098
ReferenceNA
HormoneNA
PDB IDNA