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30785 details
Primary information
ID30785
Uniprot IDP18090
DescriptionBeta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor).
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationCell membrane; multi-pass membrane protein. Note=Localized at the plasma membrane. Found in the Golg
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationHomologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
FunctionBeta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
Length466
Molecular Weight50472
ReferenceNA
HormoneNA
PDB ID2FF9;