Primary information |
---|
ID | 30780 |
Uniprot ID | P08588 |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Organism | Homo sapiens |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular Location | Cell membrane; multi-pass membrane protein. Note=Localized at the plasma membrane. Found in the Golg |
Developmental Stage | NA |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Post Translational Modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
Length | 477 |
Molecular Weight | 51323 |
Reference | NA |
Hormone | 1232; 1290 |
PDB ID | NA
|