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30780 details
Primary information
ID30780
Uniprot IDP08588
DescriptionBeta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; multi-pass membrane protein. Note=Localized at the plasma membrane. Found in the Golg
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationHomologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
FunctionBeta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
Length477
Molecular Weight51323
ReferenceNA
Hormone1232; 1290
PDB IDNA