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30778 details
Primary information
ID30778
Uniprot IDP79148
DescriptionBeta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor).
OrganismCanis familiaris
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular LocationCell membrane; multi-pass membrane protein. Note=Localized at the plasma membrane. Found in the Golg
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationHomologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
FunctionBeta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
Length473
Molecular Weight50061
ReferenceNA
HormoneNA
PDB IDNA