Detailed description page of Hmrbase2

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30430 details
Primary information
ID30430
Uniprot IDP32245
DescriptionMelanocortin receptor 4 (MC4-R).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionReceptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-; beta-; and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase.
Length332
Molecular Weight36943
ReferenceNA
HormoneNA
PDB ID2IQP; 2IQR; 2IQS; 2IQU; 2IQV; 2IQW;