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30417 details
Primary information
ID30417
Uniprot IDQ98998
Description5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A) (X5-HT1A).
OrganismXenopus laevis
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular LocationCell membrane; multi-pass membrane protein
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionThis is one of the several different receptors for 5- hydroxytryptamine (serotonin); a biogenic hormone that functions as a neurotransmitter; a hormone; and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Activation of the receptor may play a role in the exit from G0 phase and in promoting DNA synthesis.
Length408
Molecular Weight45788
ReferenceNA
HormoneNA
PDB IDNA