Detailed description page of Hmrbase2

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30327 details
Primary information
ID30327
Uniprot IDP28223
Description5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2).
OrganismHomo sapiens
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular LocationCell membrane; multi-pass membrane protein. Note=Localizes to the post-synaptic thickening of axo-de
Developmental StageNA
SimilarityBelongs to the G-protein coupled receptor 1 family.
Post Translational ModificationNA
FunctionThis is one of the several different receptors for 5- hydroxytryptamine (serotonin); a biogenic hormone that functions as a neurotransmitter; a hormone; and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction; bronchoconstriction; and control of aldosterone production.
Length471
Molecular Weight52603
ReferenceNA
Hormone1230
PDB IDNA